Yes, you can change it yourself. Ford is getting more sensible these days and put a drain plug on the pan. If you want to change the filter, you will have to drop the pan.
As far as fluid, you need to use Motorcraft Continuously Variable Chain Type Fluid. You can get this from a dealer or order it online. I doubt you will be able to find it in stores. It's going to cost $10/qt or more. Capacity is 10 quarts. So with the filter it will probably cost you about $170 to change yourself.
Ended up just taking to dealer and paid $360. Most tranny shop's didn't seem to know anything about the CVT. My fear was that they would use wrong fluid and fry it, or take it apart and not know how to put back together. That fluid is $9 a quart or more.